Description

Pentamethylenebis(Magnesium Bromide) is a highly reactive Grignard reagent, specifically a 1,5-dibromopentane-derived bis-organomagnesium compound. Its value lies in its ability to act as a versatile building block for the synthesis of five-membered carbocycles and heterocycles, introducing a C5 unit in a single step. This compound is essential for researchers and process chemists in the pharmaceutical and advanced materials sectors, where it is used to construct complex molecular frameworks with high precision and efficiency. CAS No. 23708-48-7.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing five-membered rings and spirocyclic structures in active pharmaceutical ingredients (APIs).
• Fine Chemical Production: Used in the preparation of specialty chemicals, ligands, and complex organic molecules requiring a pentamethylene bridge.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the development of novel polymers and functional materials.
• Academic & Industrial R&D: A critical tool for methodological development in organic synthesis and catalysis research.
• Agrochemical Synthesis: Employed in the creation of novel compounds with potential biological activity for crop protection.

Basic Information

Product Name	Pentamethylenebis(Magnesium Bromide)
CAS No.	23708-48-7
Molecular Formula	C5H10Br2Mg2
Molecular Weight	285.85 g/mol
Synonyms	1,5-Pentanediylbis(bromomagnesium); Magnesium, bromo(1,5-pentanediyl)di-; Pentamethylene-1,5-diylmagnesium bromide; 1,5-Dibromopentane bis-Grignard reagent; Bromopentamethylenemagnesium; (Pentane-1,5-diyl)dibromomagnesium; 1,5-Bis(bromomagnesio)pentane
EINECS	Contact for details

Quality Control

Our Pentamethylenebis(Magnesium Bromide) is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Product quality is verified through analytical techniques including titration for active magnesium content and spectroscopic methods. A Certificate of Analysis (COA) detailing purity, concentration, and solvent parameters is provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly reactive and moisture-sensitive nature, this material must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. The storage area should be cool, dry, and well-ventilated, away from sources of ignition, moisture, and oxidizing agents.

Specification

Item	Specification
Appearance	Solution (typically in THF or diethyl ether)
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.