Description

8-Bromoadenosine 3':5'-Cyclic Monophosphate is a chemically modified derivative of the crucial secondary messenger, cyclic adenosine monophosphate (cAMP). This compound matters as a potent, membrane-permeable analog and protein kinase A (PKA) activator, offering enhanced stability and specific biological activity for research applications. It is primarily needed by researchers and developers in the fields of biochemical research, pharmaceutical development, and cell signaling studies to investigate cAMP-mediated pathways.

Application

• Biochemical Research: As a potent activator of Protein Kinase A (PKA) to study intracellular signal transduction pathways.
• Pharmaceutical Development: Used as a reference standard or intermediate in the development of drugs targeting cAMP-dependent processes.
• Cell Biology Studies: To investigate the role of cAMP in cellular functions such as metabolism, gene expression, and ion channel regulation.
• Enzyme Assays: Serves as a specific substrate or modulator in enzymatic studies related to phosphodiesterases and kinases.
• Neuroscience Research: For exploring the effects of cAMP analogs on neuronal plasticity, memory, and neurotransmitter release.
• Cardiovascular Research: Used to model and study cAMP's role in heart muscle contraction and vascular tone.

Basic Information

Product Name	8-Bromoadenosine 3':5'-Cyclic Monophosphate
CAS No.	23583-48-4
Molecular Formula	C10H11BrN5O6P
Molecular Weight	392.10 g/mol
Synonyms	8-Br-cAMP; 8-Bromo-cAMP; 8-Bromoadenosine cyclic 3',5'-(hydrogen phosphate); 8-Bromo-cyclic AMP; 8-Bromoadenosine 3',5'-monophosphate; Adenosine, 8-bromo-3',5'-cyclic hydrogen phosphate; 8-Bromo-3',5'-cyclic AMP
EINECS	Contact for details

Quality Control

Our 8-Bromoadenosine 3':5'-Cyclic Monophosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.