Description

4-Ethylphenylmagnesium Bromide is a highly reactive organometallic reagent, specifically an aryl Grignard reagent, widely used in synthetic organic chemistry. Its primary value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the efficient synthesis of complex organic molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is employed in the production of active pharmaceutical ingredients (APIs), specialty chemicals, and liquid crystal intermediates.

Application

• Pharmaceutical Synthesis: A key building block for introducing the 4-ethylphenyl moiety into target molecules during the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the production of advanced herbicides, fungicides, and pesticides that require specific aryl group functionalization for enhanced activity.
• Material Science & Liquid Crystals: Serves as a critical precursor in the synthesis of organic semiconductors, OLED materials, and liquid crystal compounds for display technologies.
• Fine Chemical & Specialty Intermediates: Employed in custom synthesis and contract manufacturing for creating complex, high-value aromatic intermediates.
• Academic & Industrial R&D: A fundamental reagent in research laboratories for methodological development in cross-coupling reactions and new synthetic pathway exploration.

Basic Information

Product Name	4-Ethylphenylmagnesium Bromide
CAS No.	22873-28-5
Molecular Formula	C8H9BrMg
Molecular Weight	209.36 g/mol
Synonyms	1-Ethyl-4-magnesiobenzene Bromide; (4-Ethylphenyl)magnesium Bromide; p-Ethylphenylmagnesium Bromide; 4-Ethylbenzene, bromomagnesio-; Bromo(4-ethylphenyl)magnesium; 4-Ethylphenyl Grignard Reagent; Magnesium, bromo(4-ethylphenyl)-
EINECS	Contact for details

Quality Control

Our 4-Ethylphenylmagnesium Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Typical quality assessments include titration for Grignard concentration, GC analysis for solvent purity, and monitoring for residual magnesium. A comprehensive Certificate of Analysis (COA) detailing concentration, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. This material is highly volatile, hygroscopic (moisture-sensitive), and easily oxidized. It must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. For optimal stability and to minimize decomposition, storage at recommended cold chain conditions (2-8°C) is advised. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, water, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95%
Identification (IR)	Conforms to structure
Solvent (Typical)	Tetrahydrofuran (THF) or Diethyl Ether

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.