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(1S-3S)-β-D-3-Acetyl-1,2,3,4,6,11-Hexahydro-3,5,12-Trihydroxy-10-Me Thoxy-6,11-Dioxo-1-Naphthacenyl 2-Amino-2-Deoxyglucopyranoside CAS NO 22423-39-8
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CAS No.:22423-39-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(1S-3S)-β-D-3-Acetyl-1,2,3,4,6,11-Hexahydro-3,5,12-Trihydroxy-10-Methoxy-6,11-Dioxo-1-Naphthacenyl 2-Amino-2-Deoxyglucopyranoside is a structurally complex glycosylated anthracycline derivative, a class of compounds renowned for their potent biological activity. This high-purity chemical intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in oncology drug discovery, antibiotic development, and biochemical studies.
Application
- Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel anthracycline-based chemotherapeutic agents and antibiotics.
- Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action, structure-activity relationships (SAR), and drug resistance.
- Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research on DNA-interactive compounds.
- Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC and LC-MS assays.
- Process Chemistry Development: Utilized in scaling up and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs).
Basic Information
| Item | Details |
|---|---|
| Product Name | (1S-3S)-β-D-3-Acetyl-1,2,3,4,6,11-Hexahydro-3,5,12-Trihydroxy-10-Methoxy-6,11-Dioxo-1-Naphthacenyl 2-Amino-2-Deoxyglucopyranoside |
| CAS No. | 22423-39-8 |
| Molecular Formula | C31H34NO13 |
| Molecular Weight | 628.60 g/mol |
| Synonyms | 3'-N-Acetyldaunorubicin; 3'-N-Acetyl-13-dihydrodaunomycin; 3'-N-Acetyldaunomycin; 3'-N-Acetyl-13-dihydrodaunorubicin; 3'-N-Acetyl-13-dihydrodaunorubicinol aglycone; 3'-N-Acetyldaunorubicinol; Daunorubicin 3'-N-acetate; A derivative of Daunorubicin |
| EINECS | Contact for details |
Quality Control
Our (1S-3S)-β-D-3-Acetyl-1,2,3,4,6,11-Hexahydro-3,5,12-Trihydroxy-10-Methoxy-6,11-Dioxo-1-Naphthacenyl 2-Amino-2-Deoxyglucopyranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | Reddish-orange to orange powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Residue on Ignition | ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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