Description

2-Pyridylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis. Its core value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the construction of complex pyridine-containing molecular frameworks. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and efficient synthetic pathways.

Application

• Key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridine or bipyridine cores.
• Nucleophilic addition reactions for the production of fine chemicals and specialty agrochemicals.
• Preparation of ligands for catalysis and coordination chemistry used in material science.
• Building block for the synthesis of complex heterocyclic compounds in academic and industrial R&D.
• Used in cross-coupling reactions to introduce the 2-pyridyl group into organic molecules.

Basic Information

Product Name	2-Pyridylmagnesium Bromide
CAS No.	21970-13-8
Molecular Formula	C5H4BrMgN
Molecular Weight	176.30 g/mol
Synonyms	2-Pyridylmagnesium Bromide; Magnesium, bromo(2-pyridinyl)-; Pyridin-2-ylmagnesium Bromide; 2-Pyridyl Grignard Reagent; Bromo(2-pyridinyl)magnesium; 2-PyMgBr; 2-Pyridylmagnesium Bromide Solution
EINECS	Contact for details

Quality Control

Our 2-Pyridylmagnesium Bromide is produced under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analysis, including titration for assay determination and impurity profiling. A Certificate of Analysis (COA) detailing purity, concentration (typically supplied as a solution in THF or diethyl ether), and other critical parameters is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. This material is easily oxidized (store under inert atmosphere) and highly volatile. For solutions, store under a dry, inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. Keep away from heat, sparks, open flames, and incompatible materials such as moisture, acids, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear solution, typically colorless to light brown
Concentration	0.5 M to 2.0 M in THF or Et2O (Custom concentrations available)
Assay (Titration)	≥ 95% (as C5H4BrMgN)
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.