Description

4-Phenoxyphenylmagnesium Bromide is a high-value organometallic reagent, specifically a Grignard reagent, essential for advanced chemical synthesis. Its core value lies in its ability to act as a versatile nucleophile for introducing the 4-phenoxyphenyl moiety, enabling the construction of complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with biphenyl ether structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that require the phenoxyphenyl functional group for biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a critical reagent in the manufacture of advanced organic electronic materials for displays and lighting.
• Polymer Modification: Employed to introduce aromatic side chains into polymers to alter thermal stability, solubility, or optical properties.
• Cross-Coupling Reactions: A vital reactant in palladium-catalyzed cross-coupling reactions (e.g., Kumada coupling) for carbon-carbon bond formation.
• Fine Chemical & Specialty Chemical Production: Facilitates the synthesis of complex fragrance molecules, dyes, and other high-value specialty chemicals.

Basic Information

Product Name	4-Phenoxyphenylmagnesium Bromide
CAS No.	21473-02-9
Molecular Formula	C12H9BrMgO
Molecular Weight	273.41 g/mol
Synonyms	Magnesium, bromo(4-phenoxyphenyl)-; (4-Phenoxyphenyl)magnesium bromide; p-Phenoxyphenylmagnesium bromide; 1-Bromo-4-phenoxybenzene magnesium; Grignard reagent, 4-phenoxyphenylmagnesium bromide; 4-Phenoxybenzenemagnesium bromide; (4-Phenoxybenzene)magnesium bromide
EINECS	Contact for details

Quality Control

Our 4-Phenoxyphenylmagnesium Bromide is manufactured and handled under stringent quality systems. Each batch undergoes rigorous analytical testing, including titration for Grignard concentration and GC/HPLC analysis for purity and solvent content, to ensure consistency and reliability for sensitive synthetic applications. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its nature as an easily oxidized and highly volatile organometallic compound, it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions. The storage area should be cool, dry, and well-ventilated, away from moisture, heat, and incompatible materials.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light brown solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95% (as Grignard reagent)
Purity (GC/HPLC)	Contact for details
Solvent	Specified (Tetrahydrofuran, Diethyl ether, or Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.