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2-Methyl-1-Naphthylmagnesium Bromide CAS NO 21450-90-8
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CAS No.:21450-90-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Methyl-1-Naphthylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, essential for advanced organic synthesis. Its core value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the construction of complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.
Application
- As a key building block in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
- For the preparation of functionalized naphthalene derivatives used in material science, such as organic light-emitting diodes (OLEDs) and liquid crystals.
- In agrochemical research for constructing novel pesticide and herbicide molecules with specific activity.
- As a versatile reagent in academic and industrial R&D laboratories for exploring new catalytic cycles and reaction methodologies.
- For the introduction of the 2-methyl-1-naphthyl group into target molecules to modify physical, chemical, or biological properties.
Basic Information
| Product Name | 2-Methyl-1-Naphthylmagnesium Bromide |
| CAS No. | 21450-90-8 |
| Molecular Formula | C11H9BrMg |
| Molecular Weight | 245.40 g/mol |
| Synonyms | 1-(Bromomagnesio)-2-methylnaphthalene; (2-Methylnaphthalen-1-yl)magnesium bromide; 2-Methyl-1-naphthylmagnesium bromide solution; Grignard reagent, 2-methyl-1-naphthylmagnesium bromide; 1-Bromo-2-methylnaphthalene magnesium derivative; 2-Methyl-1-naphthyl Grignard reagent; 2-Methyl-1-naphthalenylmagnesium bromide |
| EINECS | Contact for details |
Quality Control
Our 2-Methyl-1-Naphthylmagnesium Bromide is manufactured and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as concentration (typically supplied as a solution in THF or diethyl ether), assay by titration, and impurity profile. We adhere to cGMP principles where applicable, and our quality system is designed to meet the exacting standards of advanced chemical synthesis.
Storage
Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and highly volatile, this product must be stored under a dry, inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. Keep away from moisture, heat, and incompatible materials such as acids, water, and oxidizing agents. Use only in a well-ventilated area with appropriate safety equipment.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear, colorless to light brown solution |
| Concentration | 0.5 M in THF (or as specified) |
| Assay (Titration) | ≥ 95% |
| Identification (IR/NMR) | Conforms to structure |
| Water Content (Karl Fischer) | ≤ 0.05% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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