Description

Bromo(1,1-Dimethylethyl)Magnesium is a highly reactive organomagnesium compound, commonly known as tert-Butylmagnesium bromide. This Grignard reagent is a critical building block in organic synthesis, valued for its ability to introduce the bulky tert-butyl group into target molecules with high efficiency. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable carbon-carbon bond formation. Its utility is particularly noted in the synthesis of complex molecules where steric control is paramount.

Application

• Pharmaceutical Intermediates: Key reagent for constructing complex molecular scaffolds, including active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that incorporate tert-butyl functionalities.
• Fine Chemical Manufacturing: Serves as a versatile nucleophile for the synthesis of specialty chemicals, flavors, and fragrances.
• Polymer & Material Science: Employed in the development of novel polymers, catalysts, and ligands where the tert-butyl group modifies physical or catalytic properties.
• Academic & R&D Laboratories: A fundamental tool for methodological development and exploratory synthesis in organic chemistry.
• Cross-Coupling Reactions: Acts as an efficient coupling partner in transition-metal catalyzed reactions, such as Kumada couplings.

Basic Information

Product Name	Bromo(1,1-Dimethylethyl)Magnesium
CAS No.	2259-30-5
Molecular Formula	C4H9BrMg
Molecular Weight	161.33 g/mol
Synonyms	tert-Butylmagnesium bromide; t-Butylmagnesium bromide; (1,1-Dimethylethyl)magnesium bromide; Magnesium, bromo(1,1-dimethylethyl)-; tert-C4H9MgBr; Grignard reagent, tert-butylmagnesium bromide; tert-Butyl Grignard reagent; 2-Methyl-2-propylmagnesium bromide
EINECS	Contact for details

Quality Control

Our production of Bromo(1,1-Dimethylethyl)Magnesium adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability. The product undergoes rigorous analytical testing, including titration for active magnesium content and GC analysis for solvent purity and by-products. A comprehensive Certificate of Analysis (COA) detailing assay, concentration, and impurity profiles is provided with each shipment. We operate under a quality management system to meet the exacting standards required for research and industrial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. For solutions, typical recommended storage temperature is between 2°C and 8°C. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, oxidizers, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration (in specified solvent)	Typically 1.0 M in Diethyl Ether or THF
Assay (by Titration)	≥ 95% (as Grignard reagent)
Identification (IR)	Conforms to structure
Solvent (by GC)	As specified (e.g., Diethyl Ether or THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.