Description

Fluprednidene is a synthetic corticosteroid derivative with potent anti-inflammatory and immunosuppressive properties. This compound is a critical intermediate in the synthesis of advanced pharmaceutical actives, offering significant value in the development of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel steroid-based treatments for dermatological, ophthalmic, and inflammatory conditions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent topical and systemic corticosteroids.
• Research & Development: Used in preclinical and clinical research for developing new anti-inflammatory drugs.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a precursor in the production of finished steroid APIs.
• Dermatological Preparations: Found in the development of creams and ointments for treating eczema, psoriasis, and other skin inflammations.
• Ophthalmic Solutions: Used in research for eye drops targeting inflammatory eye conditions.
• Veterinary Medicine: Employed in the development of anti-inflammatory treatments for animals.

Basic Information

Product Name	Fluprednidene
CAS No.	2193-87-5
Molecular Formula	C₂₂H₂₇FO₅
Molecular Weight	390.45 g/mol
Synonyms	Fluprednylidene; 9α-Fluoro-11β,17α,21-trihydroxy-16-methylenepregna-1,4-diene-3,20-dione; 9α-Fluoro-16-methyleneprednisolone; NSC-47439; SQ-15102; Flupredniden; Fluprednidenum
EINECS	Contact for details

Quality Control

Our Fluprednidene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-grade pharmaceutical standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.