Description

Photoclick Sphingosine CAS NO 1823021-14-2 is a specialized, high-purity sphingosine derivative engineered for advanced bioconjugation and labeling applications. Its core value lies in its unique "photoclick" chemistry, enabling rapid, selective, and bioorthogonal crosslinking under mild light irradiation, which is critical for minimizing sample perturbation. This compound is essential for researchers and developers in pharmaceutical R&D, chemical biology, and proteomics who require precise tools for studying lipid-protein interactions, cell membrane dynamics, and for developing targeted drug delivery systems.

Application

• Chemical Biology & Proteomics: As a photoreactive probe for labeling and identifying sphingolipid-binding proteins and mapping interaction networks within cells.
• Drug Delivery System Development: Functionalizing liposomes, nanoparticles, or antibody-drug conjugates (ADCs) for light-triggered, site-specific payload release.
• Biomaterial Engineering: Covalent incorporation into hydrogels or polymer scaffolds for creating bioactive, cell-instructive surfaces with spatiotemporal control.
• Lipidomics Research: Serving as a critical standard or a tagged analog for the quantitative analysis and tracking of sphingosine metabolism and signaling pathways.
• Diagnostic Reagent Synthesis: Building block for developing sensitive diagnostic assays that utilize photo-initiated capture mechanisms.
• Academic & Industrial R&D: A versatile tool for fundamental research in sphingolipid biology and for applied research in targeted therapies.

Basic Information

Product Name	Photoclick Sphingosine
CAS No.	1823021-14-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Photoactivatable Sphingosine; Light-reactive Sphingosine; Photoreactive Sphingolipid; Sphingosine Photocrosslinker; Sphingosine-based Photoprobe; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol Photoclick Derivative; CAS 1823021-14-2
EINECS	Contact for details

Quality Control

Our Photoclick Sphingosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the high standards required for sensitive research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.