Description

[1-(Trifluoromethyl)Ethenyl]-Magnesium Bromo is a highly reactive organometallic reagent, specifically a Grignard reagent, used for introducing the 1-(trifluoromethyl)ethenyl group into target molecules. This compound matters for its ability to efficiently construct complex fluorinated organic frameworks, which are critical for developing materials with enhanced stability and unique electronic properties. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for creating fluorinated active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery.
• Agrochemical Development: Used to synthesize novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of specialty fluoropolymers with high thermal and chemical resistance.
• Liquid Crystal & OLED Material Research: Employed in the synthesis of fluorinated organic semiconductors and liquid crystal compounds for electronic displays.
• Fine Chemical Manufacturing: Facilitates carbon-carbon bond formation in complex multi-step syntheses for high-value specialty chemicals.
• Cross-Coupling Reactions: Acts as a nucleophile in palladium-catalyzed reactions (e.g., Kumada coupling) to create biaryl and other complex structures.

Basic Information

Product Name	[1-(Trifluoromethyl)Ethenyl]-Magnesium Bromo
CAS No.	1418007-29-0
Molecular Formula	C3H2BrF3Mg
Molecular Weight	181.25 g/mol
Synonyms	(2,2,2-Trifluorovinyl)magnesium bromide; 1-(Trifluoromethyl)vinylmagnesium bromide; 2,2,2-Trifluoroethenylmagnesium bromide; Trifluorovinylmagnesium bromide; (Trifluorovinyl)magnesium bromide; Magnesium, bromo(2,2,2-trifluoroethenyl)-; 1-Trifluoromethylvinylmagnesium bromide
EINECS	Contact for details

Quality Control

Our [1-(Trifluoromethyl)Ethenyl]-Magnesium Bromo is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including titration for active magnesium content and GC/HPLC analysis for purity and solvent residues, to ensure consistency and reliability for sensitive synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile, hygroscopic, and easily oxidized nature, this product must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures between 2°C and 8°C. The storage area should be cool, dry, and well-ventilated, away from sources of ignition, moisture, and incompatible materials such as strong acids or oxidizing agents.

Specification

Item	Specification
Appearance	Clear to slightly colored solution
Concentration (in THF or Ether)	0.5 M - 1.0 M
Assay (by Titration)	≥ 95%
Purity (GC)	Contact for details
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.