Description

3-Cyanovinylcarbazole Phosphoramidite is a specialized monomer building block designed for the solid-phase synthesis of oligonucleotides. This compound matters for its critical role in introducing the unique carbazole moiety into nucleic acid sequences, enabling advanced research in photophysics and materials science. It is primarily needed by research institutions and pharmaceutical companies engaged in developing novel probes, sensors, and functionalized biomaterials.

Application

• Oligonucleotide Synthesis: Key monomer for the automated solid-phase synthesis of DNA/RNA strands containing carbazole-modified bases.
• Photophysical Probe Development: Used to create fluorescent or charge-transfer labels for studying nucleic acid structure and dynamics.
• Materials Science Research: Incorporation into polymers and organic semiconductors for electronic and optoelectronic applications.
• Diagnostic Assay Development: Building block for creating specialized probes used in detection and diagnostic platforms.
• Academic & Industrial R&D: Fundamental research tool in bioorganic chemistry, supramolecular chemistry, and nanotechnology.

Basic Information

Product Name	3-Cyanovinylcarbazole Phosphoramidite
CAS No.	1157899-72-3
Molecular Formula	C23H19N2O2P
Molecular Weight	386.38 g/mol
Synonyms	1-(9H-Carbazol-3-yl)-2-cyanoethenyl 2-Cyanoethyl N,N-Diisopropylphosphoramidite; 3-(2-Cyanoethenyl)-9H-carbazole 2-Cyanoethyl N,N-Diisopropylphosphoramidite; CVK Phosphoramidite; Carbazole-CE Phosphoramidite; 3-Cyanovinylcarbazole CE Phosphoramidite; N-(2-Cyanoethyl)-N-isopropyl-P-[3-(2-cyanoethenyl)-9H-carbazol-1-yl]phosphinous amide; 3-CVK Phosphoramidite
EINECS	Contact for details

Quality Control

Our 3-Cyanovinylcarbazole Phosphoramidite is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive oligonucleotide synthesis. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and moisture content. We adhere to industry-standard analytical methods to guarantee product integrity for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when opened to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in acetonitrile, dichloromethane

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.