Description

Una-U-Ce Phosphoramidite is a specialized, high-purity phosphoramidite monomer used in the synthesis of oligonucleotides. This compound is critical for researchers and manufacturers requiring precise and efficient solid-phase DNA or RNA assembly. It is an essential building block for the pharmaceutical, biotechnology, and diagnostic industries, enabling the production of antisense oligonucleotides, siRNAs, and primers for PCR and sequencing.

Application

• Oligonucleotide Synthesis: As a key monomer in automated solid-phase synthesis for research and therapeutic-grade oligonucleotides.
• Antisense Therapy Development: For the production of antisense oligonucleotides (ASOs) targeting specific mRNA sequences.
• siRNA and miRNA Synthesis: Used in the manufacture of small interfering RNA (siRNA) and microRNA (miRNA) for gene silencing applications.
• Diagnostic Probe Manufacturing: Essential for creating labeled probes used in PCR, qPCR, FISH, and microarray technologies.
• Next-Generation Sequencing (NGS): Employed in the synthesis of primers and adapters for various NGS platforms.
• Pharmaceutical R&D: Serves as a critical raw material in the development of nucleic acid-based therapeutics and vaccines.
• Academic and Contract Research: Used in university and CRO laboratories for fundamental genetic research and custom oligo production.

Basic Information

Product Name	Una-U-Ce Phosphoramidite
CAS No.	1120329-48-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5'-O-(4,4'-Dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-N4-acetyl-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite-2'-deoxycytidine; dC(Ac) Phosphoramidite (2'-O-TBDMS); N4-Acetyl-5'-O-DMT-2'-O-TBDMS-2'-deoxycytidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2'-Deoxycytidine Phosphoramidite Derivative; Una-U-Ce CE Phosphoramidite; dC Phosphoramidite (Ac, 2'-O-TBDMS); DNA Synthesis Monomer dC(Ac)
EINECS	Contact for details

Quality Control

Our Una-U-Ce Phosphoramidite is manufactured under strict quality control protocols to ensure it meets the high-purity standards required for sensitive oligonucleotide synthesis. Each batch is tested using advanced analytical techniques, including HPLC and NMR, to guarantee identity, purity, and performance. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen) due to its hygroscopic and moisture-sensitive nature. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid or foam
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Solubility	Clear, colorless solution in anhydrous acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.