Description

1-Biotinylamino-3,6,9-Trioxaundecane-11-Bromide is a specialized biotinylated polyethylene glycol (PEG) derivative, serving as a critical linker and conjugation reagent in advanced bioconjugation chemistry. Its core value lies in enabling the site-specific attachment of biotin to biomolecules, facilitating downstream purification, detection, and targeting applications. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors who require reliable, well-characterized building blocks for developing novel therapeutics and analytical assays.

Application

• Bioconjugation Reagent: For the site-specific biotinylation of peptides, proteins, antibodies, and oligonucleotides to introduce a high-affinity tag for streptavidin/avidin binding.
• Diagnostic Kit Development: Used in the manufacturing of ELISA, lateral flow assays, and other immunoassays where biotin-streptavidin signal amplification is required.
• Drug Delivery Systems: Acts as a functional linker in the synthesis of antibody-drug conjugates (ADCs) and targeted nanoparticle therapies, leveraging biotin for modular assembly.
• Affinity Purification: Enables the immobilization of biomolecules onto streptavidin-coated resins or surfaces for pull-down assays and chromatography.
• Cell Surface Labeling: Facilitates the tagging of cell surface receptors or other membrane proteins for flow cytometry and imaging studies.
• Biomaterial Functionalization: Used to modify surfaces, hydrogels, and scaffolds with biotin to create bioactive interfaces for tissue engineering and biosensing.

Basic Information

Product Name	1-Biotinylamino-3,6,9-Trioxaundecane-11-Bromide
CAS No.	1041766-91-9
Molecular Formula	C19H34BrN3O5S
Molecular Weight	496.46 g/mol
Synonyms	Biotin-PEG3-Br; Biotin-PEG3-Bromide; Biotinylated Triethylene Glycol Bromide; 11-Bromo-3,6,9-trioxa-1-azau-ndecan-1-yl)biotinamide; Biotin-amido-PEG3-Br; N-Biotinyl-3,6,9-trioxaundecane-1,11-diamine, 11-bromo derivative; Biotin-PEG3-alkyl bromide; Biotin-PEG3-propyl bromide
EINECS	Contact for details

Quality Control

Our 1-Biotinylamino-3,6,9-Trioxaundecane-11-Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and functional testing to ensure optimal performance in conjugation reactions. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines for pharmaceutical-grade materials, ensuring traceability and consistency for critical research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive). For short-term use, the material may be stored at 2-8°C in a desiccator. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.