Description

Riferminogene Pecaplasmid is a high-purity, non-viral plasmid DNA vector designed for advanced gene therapy and genetic medicine applications. This compound is critical for delivering therapeutic genes to target cells, offering a promising approach for treating genetic disorders and other complex diseases. It is primarily utilized by biopharmaceutical companies and research institutions engaged in the development of next-generation cell and gene therapies, as well as in academic research for molecular biology and genetic engineering studies.

Application

• Primary vector for non-viral gene therapy clinical trials and therapeutics.
• Research and development of ex vivo cell therapies, including CAR-T and TCR therapies.
• Critical raw material for the GMP-grade manufacturing of plasmid DNA for pharmaceutical use.
• Tool for genetic engineering and transfection studies in academic and industrial laboratories.
• Component in the development of DNA vaccines and immunotherapies.
• Use in bioprocess development and optimization for large-scale plasmid production.

Basic Information

Product Name	Riferminogene Pecaplasmid
CAS No.	1001859-46-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	pGM169 Plasmid; Riferminogene Pecaplasmid DNA; GM-169 Plasmid; pGM169 Vector; pDNA GM-169; Therapeutic Plasmid GM169; Gene Medicine 169 Plasmid; pGM169 Plasmid DNA
EINECS	Contact for details

Quality Control

Our Riferminogene Pecaplasmid is manufactured under stringent quality systems designed for pharmaceutical-grade nucleic acids. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and the absence of critical impurities such as endotoxins, host cell proteins, and residual RNA. Certificates of Analysis (COA) detailing specifications for supercoiled content, absorbance ratios, and bioburden are available upon request, supporting regulatory filings from IND to BLA stages.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C ± 5°C. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Store away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white pellet or clear, colorless solution
Identification (HPLC/Sequencing)	Conforms to reference standard
Purity (A260/A280 Ratio)	1.75 - 1.90
Assay (Supercoiled DNA Content)	≥ 90% (by HPLC)
Endotoxin	< 10 EU/mg
Bioburden	To meet Ph. Eur. 2.6.12 / USP <61>
Residual RNA	< 1.0%
Residual Protein	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.