Description

5-(3-Aminophenyl)-2’-Deoxyuridine is a modified nucleoside analog of significant interest in advanced pharmaceutical and biochemical research. This compound matters for its role as a key building block and intermediate in the synthesis of novel therapeutic agents and diagnostic probes. It is primarily needed by research institutions and pharmaceutical companies engaged in developing antiviral drugs, anticancer therapies, and molecular biology tools.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a modified building block for oligonucleotide synthesis to study DNA structure, function, and repair mechanisms.
• Probe Development: Serves as a base for creating fluorescent or radiolabeled probes for diagnostic assays and imaging studies.
• Antisense & Gene Therapy Research: Incorporated into oligonucleotides to modulate gene expression and explore therapeutic pathways.
• Enzyme Substrate Studies: Utilized to investigate the activity and inhibition of kinases, polymerases, and other nucleic acid-metabolizing enzymes.
• Library Synthesis: A valuable component for generating diverse chemical libraries in drug discovery platforms for high-throughput screening.

Basic Information

Item	Detail
Product Name	5-(3-Aminophenyl)-2’-Deoxyuridine
CAS No.	188482-60-2
Molecular Formula	C15H15N3O5
Molecular Weight	317.30 g/mol
Synonyms	5-(3-Aminophenyl)-2'-deoxyuridine; 5-(m-Aminophenyl)-2'-deoxyuridine; 2'-Deoxy-5-(3-aminophenyl)uridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(3-aminophenyl)pyrimidine-2,4-dione; 5-(3-Aminophenyl)dUrd; 5-(3-Aminophenyl)-dU; 5-(m-Aminophenyl)-dU
EINECS	Contact for details

Quality Control

Our 5-(3-Aminophenyl)-2’-Deoxyuridine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.