Description

3,5-Dimethyl-4-Methoxyphenylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, essential for forming new carbon-carbon bonds in complex organic syntheses. Its value lies in its ability to act as a nucleophile, introducing the substituted aryl moiety into target molecules with high precision and efficiency. This compound is a critical building block for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to create novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing complex drug molecules, particularly in the development of active pharmaceutical ingredients (APIs) with specific aryl-substituted frameworks.
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, fungicides, and insecticides that require the 3,5-dimethyl-4-methoxyphenyl group for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and polymers with tailored properties.
• Fine Chemical Production: Integral for the custom synthesis of high-value, low-volume specialty chemicals for research and development.
• Cross-Coupling Reactions: Acts as a coupling partner in reactions such as Kumada coupling to form biaryl structures.

Basic Information

Product Name	3,5-Dimethyl-4-Methoxyphenylmagnesium Bromide
CAS No.	185416-17-5
Molecular Formula	C9H11BrMgO
Molecular Weight	239.39 g/mol
Synonyms	4-Methoxy-3,5-dimethylphenylmagnesium bromide; (4-Methoxy-3,5-dimethylphenyl)magnesium bromide; 3,5-Dimethyl-4-methoxyphenylmagnesium bromide solution; Magnesium, bromo(4-methoxy-3,5-dimethylphenyl)-; Grignard reagent, 3,5-dimethyl-4-methoxyphenylmagnesium bromide
EINECS	Contact for details

Quality Control

Our 3,5-Dimethyl-4-Methoxyphenylmagnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analysis, including titration to determine the precise concentration of the Grignard reagent in solution. We provide Certificates of Analysis (COA) with detailed specifications, and our quality management system supports compliance with cGMP and ISO standards where required.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly reactive and moisture-sensitive nature, this product must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. The container should be kept in a cool, dry, well-ventilated area away from incompatible materials such as acids, oxidizers, and moisture sources.

Specification

Item	Specification
Appearance	Brown to dark brown solution
Concentration (in specified solvent)	0.5 M - 1.0 M (Typical in THF or Diethyl Ether)
Assay (by Titration)	≥ 95%
Solvent	Specified (e.g., Tetrahydrofuran, Diethyl ether)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.