Description

(1,3-Dioxolan-2-Ylmethyl)Magnesium Bromide is a highly reactive organomagnesium reagent, commonly known as a Grignard reagent, with the CAS number 180675-22-3. It serves as a critical building block for the efficient introduction of the 1,3-dioxolane-protected aldehyde equivalent into complex molecular frameworks. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise carbon-carbon bond formation and functional group manipulation under controlled conditions.

Application

• Pharmaceutical Intermediates: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing complex alcohol and carbonyl-containing moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific chiral centers.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances.
• Polymer & Material Science: Acts as a functional initiator or monomer modifier in the development of novel polymers with tailored properties.
• Academic & R&D Laboratories: A valuable tool for methodological development and exploratory organic synthesis in research institutions.
• Cross-Coupling Reactions: Serves as a nucleophilic partner in transition-metal catalyzed cross-coupling reactions to form new C-C bonds.

Basic Information

Product Name	(1,3-Dioxolan-2-Ylmethyl)Magnesium Bromide
CAS No.	180675-22-3
Molecular Formula	C4H7BrMgO2
Molecular Weight	191.30 g/mol
Synonyms	2-(Bromomagnesioethyl)-1,3-dioxolane; (1,3-Dioxolan-2-ylmethyl)magnesium bromide; 2-(Bromomagnesioethyl)-1,3-dioxolane solution; 1,3-Dioxolane-2-methanamine, N,N-dimethyl-, hydrochloride; Grignard reagent, (1,3-dioxolan-2-ylmethyl)magnesium bromide; (2-Bromoethyl)-1,3-dioxolane magnesium; Magnesium, bromo[(1,3-dioxolan-2-yl)methyl]-
EINECS	Contact for details

Quality Control

Our (1,3-Dioxolan-2-Ylmethyl)Magnesium Bromide is manufactured under stringent quality management systems. Each batch undergoes rigorous analytical testing, including titration for assay determination and GC/HPLC analysis for solvent and impurity profiling, to ensure consistency and high reactivity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated area. Due to its highly volatile and easily oxidized nature, the reagent is typically supplied and stored as a solution in specific anhydrous ethers (e.g., THF, diethyl ether). Keep away from heat, sparks, open flames, and incompatible materials such as moisture, acids, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to light yellow solution
Concentration	Typically 0.5 M to 2.0 M in THF or Ether
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Solvent (GC)	As specified (THF, Diethyl ether)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.