Description

Dmt-Da(Tac) Amidite 10G, Single CAS NO 149989-58-2 is a high-purity phosphoramidite monomer, a critical building block for the solid-phase synthesis of oligonucleotides. Its primary value lies in enabling the precise and efficient incorporation of modified nucleosides into DNA and RNA sequences, which is essential for advanced research and therapeutic development. This product is specifically designed for use by researchers and manufacturers in the fields of pharmaceutical development, molecular diagnostics, and biotechnology, where reliable and high-quality synthetic reagents are paramount.

Application

• Oligonucleotide Synthesis: As a key phosphoramidite reagent for the automated solid-phase synthesis of DNA and RNA strands.
• Antisense & siRNA Therapeutics: For the production of research-grade and therapeutic oligonucleotides targeting specific genes.
• Molecular Probes & Primers: Manufacturing of labeled probes and primers used in PCR, sequencing, and hybridization assays.
• Aptamer Development: Synthesis of modified DNA libraries for the selection of high-affinity aptamers.
• Diagnostic Kit Manufacturing: Production of core components for diagnostic tests, including those for infectious diseases and genetic disorders.
• Academic & Industrial R&D: Fundamental research in genomics, molecular biology, and nucleic acid chemistry.

Basic Information

Product Name	Dmt-Da(Tac) Amidite 10G, Single CAS NO 149989-58-2
CAS No.	149989-58-2
Molecular Formula	C41H49N6O8P
Molecular Weight	784.86 g/mol
Synonyms	5'-O-(4,4'-Dimethoxytrityl)-N6-(benzoyl)-2'-deoxyadenosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; DMT-dA(Bz)-CE Phosphoramidite; N6-Benzoyl-2'-deoxyadenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; DA(Bz) Phosphoramidite; dA(Bz) Amidite; 2'-Deoxyadenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
EINECS	Contact for details

Quality Control

Every batch of Dmt-Da(Tac) Amidite is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic analysis, to ensure high purity and consistency suitable for sensitive oligonucleotide synthesis applications. Certificates of Analysis (COA) detailing purity, identity, and moisture content are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (argon or nitrogen) in a dry, moisture-free environment. Due to its hygroscopic nature, allow the vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid or foam
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Clear, colorless solution in anhydrous acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.