Description

4-Methoxy-2-Methylphenylmagnesium Bromide is a versatile organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry. Its primary value lies in its ability to act as a powerful nucleophile for the formation of new carbon-carbon bonds, enabling the synthesis of complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity intermediates for constructing methoxy-substituted aromatic frameworks.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for creating active pharmaceutical ingredients (APIs) with methoxy-substituted aromatic structures.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific aryl-magnesium coupling reactions.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and material science.
• Fine Chemical Manufacturing: Employed in the production of dyes, pigments, and other specialty chemicals where methoxy-methylphenyl groups are integral.
• Academic and Industrial R&D: A critical reagent for methodological development and exploratory synthesis in organic chemistry laboratories.
• Material Science Precursor: Used in the synthesis of organic electronic materials and liquid crystals.

Basic Information

Product Name	4-Methoxy-2-Methylphenylmagnesium Bromide
CAS No.	148706-30-3
Molecular Formula	C8H9BrMgO
Molecular Weight	225.36 g/mol
Synonyms	(4-Methoxy-2-methylphenyl)magnesium bromide; 2-Methyl-4-methoxyphenylmagnesium bromide; 4-Methoxy-o-tolylmagnesium bromide; p-Methoxy-o-tolylmagnesium bromide; Grignard reagent, 4-methoxy-2-methylphenylmagnesium bromide; Magnesium, bromo(4-methoxy-2-methylphenyl)-; (2-Methyl-4-methoxyphenyl)magnesium bromide
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-Methylphenylmagnesium Bromide is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure consistency, purity, and reactivity. Certificates of Analysis (COA) detailing concentration (typically supplied as a solution in THF or diethyl ether), titration assay, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For solutions, store under a dry, inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. Keep away from heat, sparks, open flames, and strong oxidizing agents. Use appropriate explosion-proof refrigeration.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow or brown
Concentration	0.5 M in THF or Et2O (or as specified)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure
Water Content (KF)	≤ 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.