Description

3'-Deoxythymidine Diphosphate 1-Myristoyl-2-(10-Pyren-1-Yl-Decanoyl)Glycerol is a sophisticated, synthetic nucleotide-lipid conjugate designed for advanced biochemical and biophysical research. This compound is highly valued for its unique structure, which combines a modified nucleoside diphosphate with a fluorescent pyrene-labeled diacylglycerol moiety, enabling precise studies of membrane-associated processes. It is primarily utilized by researchers in academic institutions, pharmaceutical R&D, and biotechnology companies focusing on lipid signaling, enzyme kinetics, and the development of novel probes for cellular imaging.

Application

• Biochemical Research Probe: Used as a substrate or inhibitor in enzymatic studies, particularly for kinases, phosphatases, and other enzymes interacting with lipid-modified nucleotides.
• Membrane Biophysics: Serves as a critical fluorescent probe for investigating lipid bilayer dynamics, membrane protein interactions, and lipid raft formation due to the pyrene fluorophore.
• Drug Discovery Screening: Employed in high-throughput assays to identify and characterize potential therapeutic compounds that target nucleotide-lipid metabolic pathways.
• Cellular Signaling Studies: Facilitates the visualization and quantification of intracellular signaling events involving diacylglycerol analogs and nucleotide second messengers.
• Diagnostic Development: Acts as a key component in the development of sensitive diagnostic kits and assays for detecting specific enzymatic activities.

Basic Information

Product Name	3'-Deoxythymidine Diphosphate 1-Myristoyl-2-(10-Pyren-1-Yl-Decanoyl)Glycerol
CAS No.	141848-06-8
Molecular Formula	C₅₅H₇₃N₂O₁₇P₂
Molecular Weight	1091.13 g/mol
Synonyms	3'-dTDP-1-myristoyl-2-(10-pyren-1-yl-decanoyl)-sn-glycerol; Pyrene-labeled dTDP-diacylglycerol; 1-Myristoyl-2-(10-pyren-1-yl-decanoyl)-sn-glycero-3-(5'-thymidylyl) diphosphate; Fluorescent nucleotide-lipid conjugate; dTDP-PyDG; CAS 141848-06-8
EINECS	Contact for details

Quality Control

Every batch of 3'-Deoxythymidine Diphosphate 1-Myristoyl-2-(10-Pyren-1-Yl-Decanoyl)Glycerol is manufactured and analyzed under strict quality protocols to ensure the highest standards of purity and consistency for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting research-grade specifications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid or film
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Pyrene Content (UV-Vis)	Conforms to theoretical
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.