Description

Butylmagnesium Diisopropylamide 1.0 M is a highly reactive organometallic reagent, specifically a Grignard-type compound modified with a sterically hindered amide base. This product matters for its dual functionality, acting as both a strong base and a nucleophile, which is critical for advanced synthetic transformations where precise deprotonation and subsequent alkylation are required. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• As a powerful non-nucleophilic base for the deprotonation of weakly acidic C-H bonds in complex molecule synthesis.
• Key reagent in the preparation of enolates for stereoselective aldol and alkylation reactions.
• Facilitates metal-halogen exchange reactions in the synthesis of functionalized organomagnesium intermediates.
• Used in the development of active pharmaceutical ingredients (APIs) and advanced drug intermediates.
• Employed in the synthesis of ligands and catalysts for asymmetric catalysis.
• Valuable in material science for the preparation of organometallic precursors.

Basic Information

Product Name	Butylmagnesium Diisopropylamide 1.0 M
CAS No.	138858-13-6
Molecular Formula	C11H25MgN
Molecular Weight	195.63 g/mol
Synonyms	Butylmagnesium Diisopropylamide; Diisopropylaminobutylmagnesium; N-Butyl-N-(diisopropylamino)magnesium; ButylMgDA; Butylmagnesium Diisopropylamine Complex; 1.0 M Butylmagnesium Diisopropylamide Solution; Grignard Base Reagent
EINECS	Contact for details

Quality Control

Our Butylmagnesium Diisopropylamide 1.0 M is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm concentration, purity, and the absence of deleterious impurities. Certificates of Analysis (COA) detailing assay, solvent content, and other critical parameters are available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated area. Due to its moisture-sensitive and pyrophoric nature, the reagent must be handled under inert conditions using standard Schlenk-line or glovebox techniques.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Concentration	1.0 M in specified solvent (e.g., THF, Toluene)
Assay (Titration)	0.95 - 1.05 M
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.