Description

3,5-Dimethoxybenzylmagnesium Chloride is a versatile organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry. Its primary value lies in its ability to act as a powerful nucleophile and carbon source for the formation of new carbon-carbon bonds, enabling the synthesis of complex molecules. This compound is particularly essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing dimethoxy-substituted aromatic frameworks.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) containing dimethoxybenzyl motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents requiring specific aromatic architectures.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of dyes, flavors, fragrances, and other high-value specialty chemicals.
• Material Science Research: Utilized in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Academic & R&D Laboratories: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	3,5-Dimethoxybenzylmagnesium Chloride
CAS No.	135808-66-1
Molecular Formula	C9H11ClMgO2
Molecular Weight	210.94 g/mol
Synonyms	(3,5-Dimethoxybenzyl)magnesium chloride; Magnesium, chloromethylbis(3,5-dimethoxyphenyl)-; 3,5-Dimethoxybenzyl Grignard reagent; 1-(Chloromagnesio)methyl-3,5-dimethoxybenzene; (3,5-Dimethoxyphenyl)methylmagnesium chloride; 3,5-Dimethoxybenzylmagnesium chloride solution; Grignard reagent 3,5-dimethoxybenzyl chloride
EINECS	Contact for details

Quality Control

Our 3,5-Dimethoxybenzylmagnesium Chloride is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as concentration (typically supplied as a solution in THF or diethyl ether), assay, and impurity profile. We adhere to cGMP guidelines where applicable, and our quality system supports compliance with global regulatory standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For solutions, store at 2-8°C in a flammable storage cabinet. Keep away from heat, sparks, open flames, and strong oxidizers. Use appropriate ventilation and grounding procedures when handling.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identity (IR / NMR)	Conforms to structure
Water Content (KF)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.