Description

2,3-Dimethylphenylmagnesium Bromide is a highly reactive organometallic reagent, specifically an aryl Grignard reagent, widely used in fine chemical synthesis. Its core value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the efficient construction of complex organic frameworks. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and scalable synthetic methodologies.

Application

• Pharmaceutical Intermediates: Key building block for synthesizing active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials.
• Cross-Coupling Reactions: A crucial reagent in Kumada, Negishi, and other palladium-catalyzed cross-coupling reactions.
• Nucleophilic Addition Reactions: Used for adding the 2,3-dimethylphenyl group to carbonyl compounds (aldehydes, ketones, esters) and other electrophiles.

Basic Information

Product Name	2,3-Dimethylphenylmagnesium Bromide
CAS No.	134640-85-0
Molecular Formula	C8H9BrMg
Molecular Weight	209.37 g/mol
Synonyms	2,3-Dimethylphenylmagnesium Bromide; (2,3-Dimethylphenyl)magnesium Bromide; Magnesium, bromo(2,3-dimethylphenyl)-; 2,3-Dimethylphenyl Grignard Reagent; 2,3-Xylylmagnesium Bromide; Bromo(2,3-dimethylphenyl)magnesium; Grignard Reagent 2,3-DimethylphenylMgBr
EINECS	Contact for details

Quality Control

Our 2,3-Dimethylphenylmagnesium Bromide is produced under stringent quality control protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Quality is assured through comprehensive analytical testing, including titration for Grignard concentration and GC/HPLC analysis for purity and solvent content. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For optimal stability, store at 2-8°C. The solution is typically supplied in a suitable anhydrous solvent (e.g., THF or diethyl ether) and must be handled using standard Schlenk or glovebox techniques to exclude air and moisture.

Specification

Item	Specification
Appearance	Clear, colorless to light brown solution
Concentration (in THF)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95%
Solvent	Anhydrous Tetrahydrofuran (THF) or Diethyl Ether
Water Content (Karl Fischer)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.