Description

2',3'-Dideoxycytidine 5'-Triphosphate Sodium Salt is a chemically modified nucleotide triphosphate analog, specifically engineered for research and diagnostic applications. This compound is critical for enzymatic synthesis where chain termination is required, offering high specificity and purity. It is an essential reagent for molecular biologists, virologists, and pharmaceutical researchers working on nucleic acid sequencing, antiviral drug development, and related biochemical studies.

Application

• Chain-Terminating Substrate in DNA Sequencing: Used in Sanger sequencing and related enzymatic methods as a dideoxynucleotide triphosphate (ddNTP) to halt DNA strand elongation.
• Antiviral Research: Serves as a key intermediate or active metabolite in the study of nucleoside reverse transcriptase inhibitors (NRTIs) for HIV and other viral infections.
• Biochemical Assay Development: Employed in enzymatic assays to study polymerase kinetics, fidelity, and inhibition mechanisms.
• Synthesis of Nucleotide Analogs: Acts as a building block for the chemical synthesis of more complex modified nucleotides and oligonucleotides.
• Diagnostic Kit Manufacturing: Incorporated into kits for genetic testing, pathogen detection, and other molecular diagnostics that utilize chain termination principles.

Basic Information

Product Name	2',3'-Dideoxycytidine 5'-Triphosphate Sodium Salt
CAS No.	132619-66-0
Molecular Formula	C9H13N3O12P3Nan (xH2O)
Molecular Weight	Contact for details
Synonyms	ddCTP Sodium Salt; 2',3'-Dideoxycytidine-5'-triphosphate trisodium salt; Dideoxycytidine triphosphate; Zalcitabine triphosphate; ddCTP; CAS 132619-66-0; NSC 606172
EINECS	Contact for details

Quality Control

Every batch of 2',3'-Dideoxycytidine 5'-Triphosphate Sodium Salt is manufactured and tested under stringent quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive life science research. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC and other relevant methods is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (in solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (if applicable)
Biological Activity	Tested in enzymatic assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.