Description

(2-Naphthalenylmethyl)Magnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry. Its primary value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the synthesis of complex naphthalene-containing structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and efficient methods for constructing specific molecular architectures.

Application

This versatile Grignard reagent serves as a critical building block in numerous synthetic pathways. Key applications include:

• Pharmaceutical Intermediates: Synthesis of active pharmaceutical ingredients (APIs) and drug candidates featuring naphthyl or benzyl-naphthyl motifs.
• Agrochemical Synthesis: Production of herbicides, fungicides, and insecticides that incorporate naphthalene-based scaffolds for enhanced efficacy.
• Material Science Precursors: Creation of organic ligands for catalysts, monomers for specialty polymers, and components for organic electronic materials.
• Fine Chemical Manufacturing: Used in the production of dyes, pigments, and fragrances where specific naphthalene derivatives are required.
• Academic & R&D Laboratories: A fundamental tool for methodological development and exploratory synthesis in organic chemistry research.

Basic Information

Product Name	(2-Naphthalenylmethyl)Magnesium Bromide
CAS No.	127543-80-0
Molecular Formula	C11H9BrMg
Molecular Weight	245.40 g/mol
Synonyms	2-Naphthylmethylmagnesium Bromide; (2-Naphthylmethyl)magnesium Bromide; 2-(Bromomagnesio)methylnaphthalene; (2-Methylnaphthalen-1-yl)magnesium Bromide; Naphthalen-2-ylmethylmagnesium Bromide; Grignard Reagent (2-Naphthylmethyl); 2-Naphthalenemethylmagnesium Bromide; 1-(Bromomagnesio)methylnaphthalene
EINECS	Contact for details

Quality Control

Our (2-Naphthalenylmethyl)Magnesium Bromide is manufactured under stringent quality protocols. Each batch undergoes rigorous analytical testing, including titration for active Grignard concentration and analysis of key impurities, to ensure consistency and reliability for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, concentration, and solvent data is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. This material is strictly light-sensitive (protect from all light exposure), hygroscopic (moisture-sensitive), and easily oxidized (store under inert atmosphere). For optimal stability, store under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C. Keep away from strong acids and moisture.

Specification

Item	Specification
Appearance	Solution (typically in THF or Diethyl Ether)
Identification (IR/NMR)	Conforms to structure
Assay (Titration)	0.5 M to 2.0 M in solvent (custom concentrations available)
Purity (GC/HPLC)	≥ 95% (Grignard reagent)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.