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5'-Phospho-2'-Deoxyribocytidylylriboadenosine CAS NO 127067-28-1


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CAS No.:127067-28-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5'-Phospho-2'-Deoxyribocytidylylriboadenosine is a high-purity dinucleotide monophosphate, a crucial building block for advanced biochemical research and synthesis. This compound is essential for studying DNA repair mechanisms, enzyme kinetics, and as a precursor in the synthesis of oligonucleotides and nucleotide analogs. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on nucleic acid chemistry and therapeutic development.

Application

  • Biochemical Research: Critical substrate for studying DNA polymerases, ligases, and other nucleic acid-modifying enzymes.
  • Oligonucleotide Synthesis: Serves as a key phosphoramidite or solid-phase synthesis intermediate for constructing specialized DNA sequences.
  • Enzyme Kinetics & Assay Development: Used in high-throughput screening (HTS) assays to identify inhibitors or activators of nucleic acid metabolism pathways.
  • Diagnostic Reagent Manufacturing: A component in the production of probes and primers for molecular diagnostics and PCR applications.
  • Pharmaceutical R&D: Investigated as a potential precursor or metabolite in the development of antiviral and anticancer nucleotide analog drugs.
  • Standards & Calibration: Employed as a certified reference material (CRM) for quantitative analysis in mass spectrometry and chromatography.

Basic Information

Product Name 5'-Phospho-2'-Deoxyribocytidylylriboadenosine
CAS No. 127067-28-1
Molecular Formula C24H32N9O16P2
Molecular Weight 788.52 g/mol
Synonyms dCpdA; 2'-Deoxycytidylyl-(5'→5')-adenosine 5'-phosphate; Cytidylyl-adenosine phosphate; 5'-Phospho-2'-deoxycytidylyl-(5'→5')-adenosine; P-dCpdA; d(CpA) 5'-phosphate; Dinucleotide monophosphate dCpdA; Adenosine 5'-[P1-(2'-deoxy-5'-cytidylyl)]-P2-adenosine-5' ester
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Quality Control

Our 5'-Phospho-2'-Deoxyribocytidylylriboadenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification, to ensure it meets the high standards required for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Solubility Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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