Description

Himastatin CAS NO 126775-74-4 is a complex, dimeric cyclodepsipeptide natural product with significant biological activity. This compound is of high interest in pharmaceutical research and development due to its potent antitumor and antimicrobial properties. It serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers in the oncology and infectious disease therapeutic sectors.

Application

• Pharmaceutical Research: Used as a reference standard for analytical method development and validation in drug discovery pipelines.
• Oncology Drug Development: Investigated as a lead compound or intermediate for novel antitumor agents due to its mechanism of action.
• Antimicrobial Studies: Serves as a biochemical tool in research targeting drug-resistant bacterial strains.
• Biochemical Mechanism Studies: Utilized to study cell membrane interactions and apoptosis induction.
• High-Purity API Synthesis: Acts as a key building block in the synthesis of complex therapeutic candidates.
• Academic & Institutional Research: Supplied to universities and research institutes for pharmacological and chemical studies.

Basic Information

Product Name	Himastatin
CAS No.	126775-74-4
Molecular Formula	C72H98N12O18
Molecular Weight	1419.6 g/mol
Synonyms	Himastatin; FR-900405; Antibiotic FR-900405; L-156,602; (3S,6S,9S,12S,15S,18S,21S,24S,29S,32S,35S,38S)-3,6,9,12,15,18,21,24,29,32,35,38-Dodecaazatricyclo[38.6.1.1¹⁹,²⁸]octatetraconta-40,42,44,46,48,50-hexaene-4,7,10,13,16,19,22,25,30,33,36,39-dodecone
EINECS	Contact for details

Quality Control

Our Himastatin is produced and handled under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP guidelines for API intermediates where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.