Description

4-Ethoxybenzylmagnesium Chloride is a versatile organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry for the formation of carbon-carbon bonds. Its primary value lies in its ability to introduce the 4-ethoxybenzyl group into a wide array of electrophiles, enabling the synthesis of complex intermediates for pharmaceuticals and advanced materials. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build novel molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing active pharmaceutical ingredients (APIs), particularly those containing aryl-alkyl ether motifs.
• Agrochemical Development: Used in the synthesis of herbicides, fungicides, and plant growth regulators that require specific aromatic ether functionalities.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating advanced organic electronic materials with tailored optical and electronic properties.
• Fine Chemical & Fragrance Manufacturing: Employed in the synthesis of complex fragrance molecules and other high-value specialty chemicals.
• Academic & Industrial R&D: A fundamental tool for methodological development and exploratory synthesis in organic chemistry laboratories.
• Polymer Modification: Can be used to functionalize polymers or create novel monomers with specific aromatic side chains.

Basic Information

Product Name	4-Ethoxybenzylmagnesium Chloride
CAS No.	126508-26-7
Molecular Formula	C9H11ClMgO
Molecular Weight	194.94 g/mol
Synonyms	p-Ethoxybenzylmagnesium Chloride; (4-Ethoxyphenyl)methylmagnesium Chloride; 1-(Ethoxy)-4-(chloromagnesio)methylbenzene; Magnesium, chloromethyl(4-ethoxyphenyl)-; 4-Ethoxybenzylmagnesium Chloride solution; Grignard Reagent 4-EthoxybenzylMgCl
EINECS	Contact for details

Quality Control

Our 4-Ethoxybenzylmagnesium Chloride is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analysis, including titration for Grignard concentration and impurity profiling via GC or NMR. A Certificate of Analysis (COA) detailing concentration, solvent, and assay is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) to prevent decomposition. For solutions, store at 2-8°C in a dedicated, well-ventilated flammable storage area. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance (Solution)	Colorless to light yellow or brown solution
Concentration (Typical)	0.5 M to 2.0 M in THF or Diethyl Ether
Assay (Titration)	≥ 95% (of stated concentration)
Identification (NMR/IR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.