Description

Cyclopropylzinc Bromide Solution 0.5M is a versatile organometallic reagent, specifically a solution of cyclopropylzinc bromide in a suitable organic solvent. This compound is a critical building block in modern synthetic organic chemistry, enabling the efficient and selective introduction of the valuable cyclopropyl group into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the Negishi cross-coupling reaction to introduce the cyclopropyl moiety into drug candidates, a common pharmacophore.
• Agrochemical Development: Used in the synthesis of novel pesticides and herbicides containing cyclopropane rings for enhanced biological activity.
• Material Science Research: Employed in the creation of specialized organic compounds and polymers with unique electronic or structural properties.
• Catalysis & Ligand Synthesis: Serves as a precursor for creating cyclopropyl-containing ligands used in asymmetric catalysis.
• Academic & R&D Laboratories: Fundamental tool for methodological development and exploring new cyclopropanation reactions in organic synthesis.
• Fine Chemical Production: Enables the scalable manufacture of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Cyclopropylzinc Bromide Solution 0.5M
CAS No.	126403-68-7
Molecular Formula	C3H5BrZn
Molecular Weight	186.37 g/mol
Synonyms	Bromocyclopropylzinc; Cyclopropylzinc bromide; Zinc, bromocyclopropyl-; Cyclopropane, 1-bromozincio-; (Bromozincio)cyclopropane; Cyclopropyl zinc bromide; CPZnBr; 0.5M Cyclopropylzinc Bromide in THF (typical solvent)
EINECS	Contact for details

Quality Control

Every batch of our Cyclopropylzinc Bromide Solution is manufactured and analyzed under strict quality protocols to ensure consistency and reliability for sensitive synthetic applications. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing key parameters such as concentration, solvent identity, and purity. Our quality system is designed to meet the stringent requirements of research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated area. This product is highly volatile, easily oxidized, and reacts with strong acids. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Concentration	0.5 M in Tetrahydrofuran (typical)
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Solvent Content (GC)	Balance

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.