Description

m-Tolylmagnesium Chloride is a versatile organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis for the formation of carbon-carbon bonds. Its primary value lies in its ability to introduce the meta-tolyl (3-methylphenyl) group into target molecules, enabling the synthesis of complex intermediates for pharmaceuticals and advanced materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build novel aromatic structures.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing meta-substituted biphenyl and aryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the production of herbicides and fungicides that require specific tolyl-substituted aromatic cores.
• Ligand and Catalyst Preparation: Serves as a precursor for phosphine and N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored electronic properties.
• Fine Chemical Production: Facilitates the synthesis of fragrances, dyes, and other specialty chemicals where the meta-tolyl moiety is a critical structural element.
• Academic & R&D Laboratories: A fundamental tool for methodological development in organometallic and synthetic organic chemistry.

Basic Information

Product Name	m-Tolylmagnesium Chloride
CAS No.	121905-60-0
Molecular Formula	C7H7ClMg
Molecular Weight	150.89 g/mol
Synonyms	(3-Methylphenyl)magnesium Chloride; 3-Methylphenylmagnesium Chloride; m-Tolylmagnesium Chloride solution; Magnesium, chloro(3-methylphenyl)-; 3-Tolylmagnesium Chloride; meta-Tolylmagnesium Chloride; Grignard Reagent m-TolylMgCl
EINECS	Contact for details

Quality Control

Our m-Tolylmagnesium Chloride is manufactured and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including titration for Grignard concentration and GC analysis for solvent purity and by-products. A comprehensive Certificate of Analysis (COA) detailing concentration, assay, and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and moisture-sensitive nature, this product must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions. The storage area should be cool, dry, and well-ventilated, away from sources of ignition, moisture, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95%
Identification (IR)	Conforms to structure
Water Content (Karl Fischer)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.