Description

7-Hydroxyguanosine 5'-Monophosphate is a modified nucleotide monophosphate of significant interest in biochemical and pharmaceutical research. This compound serves as a critical reference standard and building block for studying nucleic acid metabolism, oxidative damage, and cellular signaling pathways. It is primarily utilized by research institutions and biotechnology companies engaged in advanced life science studies, drug discovery, and diagnostic assay development.

Application

• Biochemical Research: Used as a reference standard in the study of oxidative RNA damage and repair mechanisms.
• Pharmaceutical Development: Acts as a key intermediate or analytical standard in the research of nucleoside-based therapeutics.
• Diagnostic Assays: Employed in the development and calibration of assays for detecting biomarkers of oxidative stress.
• Enzymology Studies: Serves as a substrate or inhibitor for studying the activity of specific nucleotidases, kinases, or other nucleic acid-modifying enzymes.
• Metabolomics: Used as an analytical standard in mass spectrometry for the identification and quantification of modified nucleotides in biological samples.

Basic Information

Product Name	7-Hydroxyguanosine 5'-Monophosphate
CAS No.	119269-31-7
Molecular Formula	C10H14N5O9P
Molecular Weight	379.22 g/mol
Synonyms	7-Hydroxy-GMP; 7-OH-GMP; Guanosine, 7-hydroxy-, 5'-(dihydrogen phosphate); 7-Hydroxyguanosine 5'-phosphate; 7-Hydroxyguanosine monophosphate; 7-Hydroxy-5'-GMP; 7-Hydroxyguanosine-5'-monophosphoric acid; 5'-GMP, 7-hydroxy-
EINECS	Contact for details

Quality Control

Our 7-Hydroxyguanosine 5'-Monophosphate is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC and NMR. We adhere to relevant industry standards for research chemicals to guarantee reliable performance in your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under desiccant when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.