Description

Poly(Deoxyinosinic-Deoxycytidylic) Acid is a synthetic, double-stranded polynucleotide composed of alternating deoxyinosinic and deoxycytidylic acid residues. This compound serves as a critical research-grade nucleic acid polymer, primarily utilized as a model for studying DNA structure, protein-nucleic acid interactions, and immune system activation. It is essential for biopharmaceutical R&D, molecular biology, and immunology laboratories requiring high-purity, defined-sequence polynucleotides for diagnostic and therapeutic development.

Application

• Immunological Research: Used as a synthetic ligand for studying Toll-like receptor (TLR) signaling pathways and innate immune responses.
• Molecular Biology: Serves as a substrate or competitor in enzymatic assays for nucleases, polymerases, and helicases.
• Biopharmaceutical Development: Employed in the research and development of nucleic acid-based vaccines and immunotherapies.
• Diagnostic Reagent Formulation: Acts as a component in control samples and calibration standards for molecular diagnostic kits.
• Biochemical Standard: Provides a reference material for spectroscopic analysis and quantification of nucleic acids.
• Academic Research: Fundamental tool for investigating the biophysical properties and interactions of double-stranded DNA analogs.

Basic Information

Product Name	Poly(Deoxyinosinic-Deoxycytidylic) Acid
CAS No.	118578-37-3
Molecular Formula	(C10H13N4O7P • C9H13N3O7P)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly(dI-dC); Poly(deoxyinosinic-deoxycytidylic) acid sodium salt; Poly(dI-dC)•Poly(dI-dC); Poly(deoxyinosinic-deoxycytidylic) acid duplex; Poly(dI-dC) duplex; Alternating poly(dI-dC); Synthetic double-stranded DNA polymer; Poly(dI-dC) sodium salt
EINECS	Contact for details

Quality Control

Our Poly(Deoxyinosinic-Deoxycytidylic) Acid is manufactured under stringent conditions to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as absorbance ratios, endotoxin levels, and bioburden. We adhere to ISO 9001 quality management principles, and our processes are designed to support compliance with cGMP guidelines for research-use materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term stability, store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white fibrous solid or lyophilized powder
Identification (UV-Vis)	Characteristic absorbance maxima at ~248-252 nm
A260/A280 Ratio	1.8 - 2.0
Assay (HPLC)	≥ 95% (Polymer Content)
Endotoxin	< 10 EU/mg
Solubility	Soluble in TE buffer or sterile water for injection
Bioburden	< 100 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.