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4-Methoxy-3-Methylphenylmagnesium Bromide CAS NO 117896-10-3
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CAS No.:117896-10-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-Methoxy-3-Methylphenylmagnesium Bromide is a highly reactive Grignard reagent, a cornerstone organometallic compound for constructing complex molecular architectures. Its primary value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, a critical step in the synthesis of fine chemicals and advanced intermediates. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for complex organic synthesis.
Application
- Pharmaceutical Intermediate Synthesis: A key reagent for introducing the 4-methoxy-3-methylphenyl moiety into target molecules during the development of active pharmaceutical ingredients (APIs).
- Agrochemical Manufacturing: Used in the synthesis of advanced herbicide and pesticide intermediates that require specific aryl group functionalization.
- Ligand and Catalyst Preparation: Serves as a precursor for the synthesis of specialized ligands used in homogeneous catalysis and material science.
- Fine Chemical Production: Employed in the multi-step synthesis of complex organic compounds for flavors, fragrances, and electronic chemicals.
- Academic and R&D Laboratories: A vital tool for methodological development and exploratory synthesis in organic chemistry research.
- Material Science Research: Used to create novel organic building blocks for polymers and advanced functional materials.
Basic Information
| Product Name | 4-Methoxy-3-Methylphenylmagnesium Bromide |
| CAS No. | 117896-10-3 |
| Molecular Formula | C8H9BrMgO |
| Molecular Weight | 225.36 g/mol |
| Synonyms | (4-Methoxy-3-methylphenyl)magnesium bromide; 3-Methyl-4-methoxyphenylmagnesium bromide; 4-Methoxy-m-tolylmagnesium bromide; Magnesium, bromo(4-methoxy-3-methylphenyl)-; Grignard reagent, 4-methoxy-3-methylphenylmagnesium bromide |
| EINECS | Contact for details |
Quality Control
Our 4-Methoxy-3-Methylphenylmagnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as concentration (typically supplied as a solution in THF or diethyl ether), assay, and impurity profile. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the exacting standards of the pharmaceutical and fine chemical industries.
Storage
Preserve in a tightly closed container, protected from light. Due to its highly reactive and moisture-sensitive nature, this product must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. The container must be kept tightly sealed in a cool, dry, and well-ventilated area, away from sources of ignition, moisture, and incompatible materials such as acids, oxidizers, and protic solvents.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear, colorless to light brown solution |
| Concentration | Typically 0.5M to 1.0M in THF or Diethyl Ether |
| Assay (Titration) | ≥ 95% (as Grignard reagent) |
| Identification (IR) | Conforms to structure |
| Water Content (KF) | < 100 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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