Description

Tetracenomycin B3 is a specialized anthracycline-type polyketide antibiotic and a key intermediate in the biosynthesis of tetracycline antibiotics. This compound matters for its role as a critical building block in pharmaceutical research and development, particularly for studying antibiotic synthesis pathways and developing novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on antibiotic discovery, microbial chemistry, and metabolic engineering.

Application

• Pharmaceutical Research & Development: Serves as a crucial biosynthetic intermediate and reference standard in the study of tetracycline and anthracycline antibiotic pathways.
• Antibiotic Discovery: Used as a molecular scaffold or precursor in the synthesis and development of new antibiotic candidates with modified biological activity.
• Biochemical Studies: Employed in enzymatic studies to investigate polyketide synthase (PKS) mechanisms and the tailoring steps in natural product biosynthesis.
• Microbial Metabolism Research: Acts as a tool compound for understanding secondary metabolite production in Streptomyces and other actinobacteria.
• Academic & Industrial Reference Standard: Provides a high-purity standard for analytical method development, quality control, and identification in related chemical processes.

Basic Information

Product Name	Tetracenomycin B3
CAS No.	117241-62-0
Molecular Formula	C22H18O9
Molecular Weight	426.37 g/mol
Synonyms	Tetracenomycin B3; Tcm B3; 4,8,10-Trihydroxy-3-methyl-1,2,3,4,4a,12b-hexahydrotetracene-5,6,11,12-tetrone; (4aS,12bS)-4,8,10-Trihydroxy-3-methyl-1,2,3,4,4a,12b-hexahydrotetracene-5,6,11,12-tetrone; Tetracenomycin B3 (TcmB3); Antibiotic Tcm B3
EINECS	Contact for details

Quality Control

Our Tetracenomycin B3 is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity determination and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.