Description

5-[(1E)-3-Amino-1-Propen-1-Yl]-2'-Deoxyuridine 5'-(Tetrahydrogen Triphosphate) is a modified nucleoside triphosphate analog, a critical building block for advanced biochemical research and development. This compound is valued for its role in probing and manipulating nucleic acid structure and function, particularly in enzymatic studies and the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in molecular biology, enzymology, and antiviral or anticancer drug discovery.

Application

• Enzymatic Substrate Studies: Used as a substrate for DNA polymerases and reverse transcriptases to study enzyme kinetics, fidelity, and inhibition mechanisms.
• Nucleic Acid Labeling & Sequencing: Employed in the enzymatic incorporation of modified bases for labeling DNA probes or in next-generation sequencing technologies.
• Antiviral & Anticancer Research: Serves as a precursor or active metabolite in the development of nucleoside analog prodrugs targeting viral replication or cellular proliferation.
• Structural Biology: Incorporated into oligonucleotides for X-ray crystallography or NMR studies to investigate nucleic acid-protein interactions.
• Diagnostic Assay Development: Utilized in the synthesis of specialized primers and probes for sensitive molecular diagnostic tests.

Basic Information

Item	Detail
Product Name	5-[(1E)-3-Amino-1-Propen-1-Yl]-2'-Deoxyuridine 5'-(Tetrahydrogen Triphosphate)
CAS No.	116840-18-7
Molecular Formula	C₁₂H₁₉N₄O₁₄P₃
Molecular Weight	560.22 g/mol
Synonyms	5-(3-Amino-1-propenyl)-2'-deoxyuridine 5'-triphosphate; 5-(E)-3-Aminoprop-1-en-1-yl-2'-deoxyuridine triphosphate; dUTP analog; Modified dUTP triphosphate; 5-Aminopropenyl-dUTP; 5-(3-Aminoprop-1-enyl)-dUTP; 5-[(E)-3-Aminoprop-1-en-1-yl]-2'-deoxyuridine 5'-triphosphate
EINECS	Contact for details

Quality Control

Our production of this high-purity biochemical adheres to stringent quality protocols. Each batch is characterized by HPLC, NMR, and mass spectrometry to confirm identity and purity, ensuring it meets the exacting standards required for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and concentration is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the material desiccated and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.