Description

5-Propargylamino-Dctp is a specialized nucleoside analog derivative, a key building block in advanced biochemical research and synthesis. This compound is valued for its unique propargylamino modification, which enables click chemistry applications and serves as a versatile intermediate. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors. Its precise structure makes it essential for developing novel therapeutic agents and molecular probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Bioconjugation & Click Chemistry: The propargylamino group facilitates Huisgen cycloaddition reactions for labeling biomolecules like DNA and proteins.
• Molecular Biology Research: Used in the study of nucleic acid metabolism, enzyme mechanisms, and as a substrate for DNA polymerases.
• Diagnostic Probe Development: Incorporated into oligonucleotide probes for fluorescence in situ hybridization (FISH) and other detection assays.
• Biochemical Tool Compound: Serves as a research tool for investigating nucleotide processing pathways and cellular signaling.
• Precision Chemical Synthesis: Employed in the controlled synthesis of modified oligonucleotides with specific functional properties.

Basic Information

Product Name	5-Propargylamino-Dctp
CAS No.	115899-39-3
Molecular Formula	C13H17N4O13P3
Molecular Weight	554.22 g/mol
Synonyms	5-(2-Propynylamino)-2'-deoxycytidine-5'-triphosphate; 5-Propargylamino-2'-deoxycytidine triphosphate; 5-Propargylamino-dCTP; 5-Propargylaminodeoxycytidine triphosphate; Propargylamino-dCTP; 5-PA-dCTP; dCTP-Propargylamine; N4-(2-Propynyl)-2'-deoxycytidine-5'-triphosphate
EINECS	Contact for details

Quality Control

Our 5-Propargylamino-Dctp is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.