Description

2'-Deoxyguanylyl(3'->5')-2'-Deoxyguanosine Sodium Salt is a high-purity dinucleoside monophosphate, a critical building block in oligonucleotide synthesis. This compound is essential for researchers and manufacturers developing advanced nucleic acid-based therapeutics, diagnostics, and research tools. It is primarily utilized in the pharmaceutical, biotechnology, and life science research sectors for the precise construction of DNA sequences.

Application

• Oligonucleotide Synthesis: A key phosphoramidite or solid-phase synthesis precursor for constructing specific DNA sequences.
• Pharmaceutical Research: Used in the development of antisense oligonucleotides, siRNA, aptamers, and other gene-targeting therapeutic agents.
• Diagnostic Probe Development: Essential for manufacturing labeled probes used in PCR, qPCR, FISH, and microarray technologies for genetic testing and pathogen detection.
• Biochemical Research: Serves as a substrate or standard in enzymatic studies, including those involving polymerases, nucleases, and ligases.
• CRISPR/Cas9 System Components: Used in the synthesis of guide RNAs (gRNAs) and other nucleic acid components for gene editing applications.
• Standards and Calibrants: Acts as a high-purity reference standard in analytical laboratories for quality control and method validation.

Basic Information

Product Name	2'-Deoxyguanylyl(3'->5')-2'-Deoxyguanosine Sodium Salt
CAS No.	113753-10-9
Molecular Formula	C20H24N10O11PNa
Molecular Weight	634.43 g/mol
Synonyms	d(pGpG) sodium salt; GpG sodium salt; Deoxyguanylyl-deoxyguanosine sodium; pdGpdG sodium salt; Dinucleoside monophosphate; 2'-Deoxy-Guanosine-5'-monophospho-(3'→5')-2'-deoxy-Guanosine sodium salt; dGpdG sodium salt; Guanylyl(3'→5')guanosine sodium salt (deoxy form)
EINECS	Contact for details

Quality Control

Our 2'-Deoxyguanylyl(3'->5')-2'-Deoxyguanosine Sodium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.