Description

Saframycin Mx1 CAS NO 113036-78-5 is a potent quinone-containing antibiotic compound belonging to the saframycin family. This compound is valued for its significant biological activity, particularly as a DNA-binding agent and topoisomerase inhibitor, making it a critical intermediate and reference standard in pharmaceutical research and development. It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel anti-cancer and antimicrobial agents.

Application

• As a key pharmaceutical reference standard for analytical method development and validation.
• As a biochemical research tool for studying DNA interaction mechanisms and topoisomerase inhibition.
• As a precursor or intermediate in the synthesis of more complex saframycin analogs and derivatives.
• In anti-cancer research for evaluating cytotoxic activity against various tumor cell lines.
• In antibiotic research for investigating its mechanism of action against resistant bacterial strains.
• For use in academic and industrial R&D programs focused on natural product chemistry and drug discovery.

Basic Information

Product Name	Saframycin Mx1
CAS No.	113036-78-5
Molecular Formula	C28H30N4O7
Molecular Weight	534.56 g/mol
Synonyms	Saframycin MX1; Antibiotic C-15003 Mx1; NSC 366140; (1S,13S,14S,26S,27S,28S)-14,27-Diethyl-5,8,16,19,22-pentaoxo-1,2,3,4,5,6,7,8,9,10,15,16,17,18,19,20,25,26,27,28,29,30-docosahydro-1,13:14,26-dietheno-13H,28H-dipyrido[2,1-f:3',2',1'-ij][1,7,12,17]benzoxatetraazacyclodocosine-11,24-dicarbonitrile
EINECS	Contact for details

Quality Control

Our Saframycin Mx1 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.