Description

Carbocyclic 5-(2-Bromovinyl)-2'-Deoxyuridine 5'-Triphosphate is a modified nucleoside triphosphate analog, a critical building block for advanced biochemical and pharmaceutical research. This compound matters for its role as a potent antiviral agent precursor and as a specialized substrate for DNA polymerases in molecular biology applications. It is primarily needed by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in antiviral drug development, nucleotide-based probe synthesis, and enzymatic studies.

Application

• Antiviral Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel nucleoside analog antiviral agents.
• Molecular Biology & Biochemistry: Used as a modified substrate for DNA polymerases (e.g., in PCR or primer extension assays) to study enzyme kinetics, fidelity, or to incorporate specific labels.
• Diagnostic Probe Synthesis: Employed in the enzymatic synthesis of labeled DNA probes for detecting specific viral sequences or genetic markers.
• Enzymology Studies: Acts as a tool compound to investigate the mechanisms and inhibition of viral or cellular polymerases.
• Radiopharmaceutical Precursor: Can be used as a starting material for synthesizing radiolabeled (e.g., with tritium or carbon-14) versions for pharmacokinetic and metabolic studies.
• Bioconjugation & Labeling: The reactive bromovinyl group provides a handle for further chemical modifications and conjugations for creating targeted molecular tools.

Basic Information

Product Name	Carbocyclic 5-(2-Bromovinyl)-2'-Deoxyuridine 5'-Triphosphate
CAS No.	111634-67-4
Molecular Formula	C₁₆H₂₁BrN₃O₁₃P₃
Molecular Weight	660.17 g/mol
Synonyms	c-BVDU-TP; Carbocyclic BVDU-TP; (E)-5-(2-Bromovinyl)-1-[(1S,4R)-4-hydroxy-2-cyclopenten-1-yl]uracil 5'-triphosphate; 5-(2-Bromovinyl)-2'-deoxyuridine 5'-triphosphate carbocyclic analog; cBVdUTP; Carbocyclic 5-Bromovinyldeoxyuridine Triphosphate; BrVDU-TP (carbocyclic)
EINECS	Contact for details

Quality Control

Our Carbocyclic 5-(2-Bromovinyl)-2'-Deoxyuridine 5'-Triphosphate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the material under an inert atmosphere or desiccated to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.