Description

4'-(Aminomethyl)-3',6'-Dihydroxy-3H-Spiro-[Isobenzofuran-1,9'-Xanthen]-3-One is a specialized organic compound belonging to the xanthene dye family, characterized by its unique spirocyclic structure and functional groups. This compound matters as a versatile chemical intermediate and a potential precursor for synthesizing advanced fluorescent probes and labeling reagents used in life sciences research. It is primarily needed by manufacturers and R&D teams in the pharmaceutical, biotechnology, and diagnostic sectors for developing sensitive detection assays and novel imaging agents.

Application

• Fluorescent Probe Synthesis: A key intermediate for creating advanced fluorescent dyes and molecular tags used in bioimaging and cellular analysis.
• Bioconjugation & Labeling Reagents: Serves as a precursor for developing amine-reactive probes for labeling proteins, antibodies, and nucleic acids.
• Diagnostic Assay Development: Used in research to formulate sensitive components for ELISA, lateral flow assays, and other diagnostic platforms.
• Chemical Biology Research: Employed as a building block for designing activity-based probes to study enzyme function and cellular processes.
• Sensor Material Fabrication: A potential component in the development of optical chemical sensors for detecting specific analytes.
• Pharmaceutical Intermediate: May be utilized in the synthetic pathways of certain active pharmaceutical ingredients (APIs) requiring a xanthene core.

Basic Information

Item	Details
Product Name	4'-(Aminomethyl)-3',6'-Dihydroxy-3H-Spiro-[Isobenzofuran-1,9'-Xanthen]-3-One
CAS No.	106754-95-4
Molecular Formula	C22H17NO5
Molecular Weight	375.38 g/mol
Synonyms	3',6'-Dihydroxy-4'-(aminomethyl)-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one; 4'-Aminomethylfluorescein; 5-(and-6)-(((Aminomethyl)fluorescein)thiourea; AMF; Aminomethylfluorescein; Fluoresceinamine isomer; Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4'-(aminomethyl)-3',6'-dihydroxy-
EINECS	Contact for details

Quality Control

Our 4'-(Aminomethyl)-3',6'-Dihydroxy-3H-Spiro-[Isobenzofuran-1,9'-Xanthen]-3-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets precise customer specifications. Certificates of Analysis (COA) detailing all quality parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.