Description

Kinase (Phosphorylating), Phosphatidylinositol 4-Phosphate 5- is a high-purity biochemical reagent essential for studying intracellular signaling pathways, particularly those involving phosphoinositide metabolism. This compound serves as a critical substrate for specific kinases and phosphatases, enabling researchers to elucidate mechanisms in cell growth, proliferation, and membrane trafficking. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on oncology, metabolic disorders, and neurological disease research.

Application

• Enzymology Research: As a defined substrate for in vitro kinase and phosphatase activity assays.
• Signal Transduction Studies: Investigating the role of phosphoinositides in cellular signaling cascades.
• Drug Discovery & Screening: Target compound for high-throughput screening (HTS) of potential therapeutic inhibitors.
• Biochemical Standard: Used as a reference standard in analytical methods like HPLC and mass spectrometry for quantification.
• Lipidomics: A key component in profiling cellular lipid composition and metabolism.
• Cell Biology: Studying membrane dynamics, vesicle transport, and cytoskeletal organization.

Basic Information

Product Name	Kinase (Phosphorylating), Phosphatidylinositol 4-Phosphate 5-
CAS No.	104645-76-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PI(4)P5-Kinase Substrate; Phosphatidylinositol 4,5-bisphosphate precursor; PtdIns(4)P; 1-Phosphatidyl-1D-myo-inositol 4-phosphate; PI4P; L-α-Phosphatidylinositol 4-phosphate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing specific lot results are available upon request. We adhere to a quality management system suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This material is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform/methanol mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.