Description

Adenosine 5'-o-Thiomonophosphate Dilithium Salt is a chemically modified nucleotide analog where a sulfur atom replaces an oxygen atom in the phosphate group, offering unique biochemical properties. This modification makes it a valuable tool in enzymatic studies, particularly as a substrate or inhibitor for kinases and other ATP-binding enzymes. It is essential for researchers and manufacturers in pharmaceutical development, biochemical research, and diagnostic assay production who require high-purity nucleotide derivatives for probing cellular signaling pathways.

Application

• Biochemical Research: Used as a substrate analog in enzymatic assays to study kinase activity, ATPase function, and phosphotransfer mechanisms.
• Pharmaceutical Screening: Serves as a key component in high-throughput screening (HTS) platforms to identify potential enzyme inhibitors for drug discovery.
• Diagnostic Reagents: Incorporated into kits for measuring enzymatic activity in clinical and research settings.
• Metabolic Pathway Studies: Employed to investigate the role of nucleotide derivatives in cellular energy metabolism and signaling cascades.
• Proteomics & Molecular Biology: Utilized in protein labeling and cross-linking experiments due to its modified phosphate backbone.
• Reference Standard: Acts as a certified reference material (CRM) for quality control in the production of nucleotide-based products.

Basic Information

Item	Details
Product Name	Adenosine 5'-o-Thiomonophosphate Dilithium Salt
CAS No.	19341-57-2
Molecular Formula	C10H12Li2N5O6PS
Molecular Weight	375.15 g/mol
Synonyms	Adenosine 5'-(Thiomonophosphate) Dilithium Salt; Adenosine-5'-O-thiomonophosphate Li2 salt; AMP-S Dilithium Salt; 5'-O-Thiophosphoadenosine Dilithium Salt; Adenosine 5'-monothiophosphate Dilithium Salt; 9-β-D-Ribofuranosyladenine 5'-(dihydrogen thiophosphate) Dilithium Salt; ATP-α-S analog (dilithium salt)
EINECS	Contact for details

Quality Control

Every batch of our Adenosine 5'-o-Thiomonophosphate Dilithium Salt is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.