Description

(7R)-8-Ethyl-7,8,9,10-Tetrahydro-1,4,6,7β,8α,10α,11-Heptahydroxy-5,12-Naphthacenedione CAS NO 17514-32-8 is a complex, polyhydroxylated naphthacenedione derivative, a chemical class known for its significant biological and chemical activity. This compound matters as a high-purity, structurally defined intermediate crucial for advanced research and synthesis in pharmaceutical development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of novel therapeutic agents and as a reference standard.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel anthracycline and tetracycline analogs for anticancer and antibiotic research.
• Biochemical Research: Used as a reference standard and probe in studies of DNA intercalation, topoisomerase inhibition, and redox biology.
• Fine Chemical Synthesis: Serves as a versatile precursor for the development of complex, polycyclic molecules with potential biological activity.
• Academic Research: Employed in university and institutional labs for mechanistic studies and the development of new synthetic methodologies.
• Process Chemistry: Used in scale-up and optimization studies for the production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(7R)-8-Ethyl-7,8,9,10-Tetrahydro-1,4,6,7β,8α,10α,11-Heptahydroxy-5,12-Naphthacenedione
CAS No.	17514-32-8
Molecular Formula	C₂₂H₂₄O₉
Molecular Weight	432.42 g/mol
Synonyms	8-Ethyl-7,8,9,10-tetrahydro-1,4,6,7,8,10,11-heptahydroxy-5,12-naphthacenedione, (7R)- form; 7-Deoxy-13-dihydrodaunomycinone; 7R-8-Ethyl-7,8,9,10-tetrahydro-1,4,6,7,8,10,11-heptahydroxy-5,12-naphthacenedione; Arugomycin F; 7-Deoxy-13-dihydrocarminomycinone; Arugomycin aglycone derivative; 7R-Hexahydroxyethyltetrahydroanthraquinone derivative. Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (7R)-8-Ethyl-7,8,9,10-Tetrahydro-1,4,6,7β,8α,10α,11-Heptahydroxy-5,12-Naphthacenedione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and ensure long-term stability. Keep the container sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Orange to red-brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.