Description

17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione is a high-purity synthetic steroid derivative with a complex polycyclic structure. This compound serves as a critical pharmaceutical intermediate and a valuable building block in advanced organic synthesis, enabling the development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potent corticosteroid analogs and other biologically active steroid molecules.
• Research & Development: Used as a reference standard and starting material in medicinal chemistry programs for exploring new anti-inflammatory or hormonal therapies.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Biochemical Research: Investigated for its interactions with steroid hormone receptors to study structure-activity relationships (SAR).
• Custom Synthesis: Serves as a specialized substrate for the production of tailored steroid derivatives for specific client applications.

Basic Information

Product Name	17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione
CAS No.	13504-15-9
Molecular Formula	C22H28O4
Molecular Weight	356.46 g/mol
Synonyms	16β-Methylprednisolone; 16β-Methyl-δ1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione; 16β-Methyl-1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione; 16β-Methyl-17α,21-dihydroxypregna-1,4,9(11)-triene-3,20-dione; 16β-Methylprednisolone (δ9(11) derivative); 9(11)-Dehydroprednisolone 16β-methyl derivative
EINECS	Contact for details

Quality Control

Our 17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets exacting standards for research and pharmaceutical use. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.