Description

Bleomycin CAS NO 11056-06-7 is a complex glycopeptide antibiotic mixture, primarily composed of bleomycin A2 and B2, known for its potent antitumor activity. This compound is a critical active pharmaceutical ingredient (API) used in the formulation of chemotherapeutic agents. It is essential for pharmaceutical manufacturers, research institutions, and biotechnology companies involved in oncology drug development and production.

Application

• Oncological Pharmaceutical Formulations: Primary API in injectable chemotherapy drugs for treating various cancers, including Hodgkin's lymphoma, testicular cancer, and squamous cell carcinomas.
• Clinical Research & Drug Development: Used in preclinical and clinical studies to investigate mechanisms of action, efficacy, and new combination therapies.
• Biochemical Research: Employed as a tool compound to study DNA cleavage, cell cycle arrest, and apoptosis in molecular biology laboratories.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical testing laboratories.
• Veterinary Oncology: Potential use in the development of chemotherapeutic treatments for animals.

Basic Information

Item	Detail
Product Name	Bleomycin
CAS No.	11056-06-7
Molecular Formula	C55H84N17O21S3 (Bleomycin A2)
Molecular Weight	Approx. 1415.55 g/mol (Bleomycin A2)
Synonyms	Bleomycin Sulfate; Blenoxane; Bleo; Bleomycin A2; Bleomycin B2; NSC-125066; U-30673; Antibiotic U-30673
EINECS	234-296-0

Quality Control

Our Bleomycin is manufactured and tested under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and composition, to ensure it meets stringent pharmaceutical-grade specifications. A detailed Certificate of Analysis (COA) documenting identity, purity, potency, and related substances is provided with every shipment to support regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	NLT 95.0% (sum of Bleomycin A2 & B2)
Composition (A2/B2 Ratio)	Specified per customer requirement
Water Content (KF)	NMT 5.0%
pH (in solution)	4.5 - 6.0
Bacterial Endotoxins	< 1.0 EU/mg
Sterility (if supplied sterile)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.