Description

Methyl 4-[4-dimethylamino-5-[4-hydroxy-6-methyl-5-(6-methyl-5-oxo-oxan-2-yl)oxy-oxan-2-yl]oxy-6-methyl-oxan-2-yl]oxy-2-ethyl-2,5-dihydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate is a complex, semi-synthetic tetracycline derivative of significant interest in advanced pharmaceutical research and development. This compound matters for its potential as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of next-generation antimicrobial and anti-inflammatory agents. It is primarily needed by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the development of novel therapeutic compounds, particularly within the antibiotic and specialty medicine sectors.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel tetracycline-class antibiotics.
• Active Pharmaceutical Ingredient (API) Research: Used in preclinical and clinical research for developing new antibacterial therapies targeting resistant pathogens.
• Biochemical Research: Employed in studies investigating protein synthesis inhibition and mechanisms of antibiotic action.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Acts as a specialized substrate for further chemical modifications to explore structure-activity relationships (SAR).

Basic Information

Product Name	Methyl 4-[4-dimethylamino-5-[4-hydroxy-6-methyl-5-(6-methyl-5-oxo-oxan-2-yl)oxy-oxan-2-yl]oxy-6-methyl-oxan-2-yl]oxy-2-ethyl-2,5-dihydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate
CAS No.	87080-93-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline methyl ester; Methacycline derivative; 6-Methylene-5-oxytetracycline methyl ester; 6-Deoxy-6-demethyl-6-methylene-5-OXYTC methyl ester; Tetracycline intermediate 87080-93-1; 6-Methylene-5-OXYTC methyl ester; Antibiotic research intermediate; 6-Demethyl-6-deoxy-6-methylene-5-oxytetracycline methyl ester
EINECS	Contact for details

Quality Control

Our methyl 4-[4-dimethylamino-5-[4-hydroxy-6-methyl-5-(6-methyl-5-oxo-oxan-2-yl)oxy-oxan-2-yl]oxy-6-methyl-oxan-2-yl]oxy-2-ethyl-2,5-dihydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet the requirements of cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) or as specified on the label or COA. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.