Description

5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-8,11-dihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, hydrochloride (1:1), (8S,10S)- is a complex, high-purity chemical derivative of the anthracycline class. This compound is of significant interest for its role as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily sought by R&D teams and quality control laboratories in the pharmaceutical and biotechnology sectors for the synthesis and analysis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of specialized anthracycline-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity certified standard for analytical method development, validation, and quality control (QC) testing in pharmaceutical manufacturing.
• Biochemical Research: Serves as a tool compound in life science research to study structure-activity relationships (SAR) and biological mechanisms.
• Process Development: Employed in the development and optimization of scalable synthetic routes for complex molecules in process chemistry.

Basic Information

Product Name	5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-8,11-dihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, hydrochloride (1:1), (8S,10S)-
CAS No.	73952-94-0
Molecular Formula	C26H30ClNO11
Molecular Weight	568.0 g/mol (approx.)
Synonyms	10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride; 4-Demethoxy-7-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)adriamycinone hydrochloride; Related to Idarubicin and Daunorubicin derivatives; Anthracycline glycoside derivative hydrochloride salt; (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your research and development needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Our quality systems are designed to meet the stringent requirements for pharmaceutical intermediates and reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.