Description

10-(4-amino-5-hydroxy-6-methyl-oxan-2-yl)oxy-8-[N-(hexan-2-ylideneamino)-C-methyl-carbonimidoyl]-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione hydrochloride is a complex, high-purity chemical intermediate of significant interest in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the development of novel therapeutic agents, particularly within the anthracycline and tetracycline derivative classes. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new antibiotics and targeted cancer therapies, where precise molecular architecture is critical for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel anthracycline-based antibiotic and chemotherapeutic agents.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and the creation of new molecular entities targeting bacterial and cancer cells.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in multi-step synthetic routes for the production of complex, high-value active pharmaceutical ingredients.
• Biochemical Research: Utilized as a standard or probe in biochemical assays to study DNA intercalation and topoisomerase inhibition mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized tetracyclic frameworks.

Basic Information

Item	Detail
Product Name	10-(4-amino-5-hydroxy-6-methyl-oxan-2-yl)oxy-8-[N-(hexan-2-ylideneamino)-C-methyl-carbonimidoyl]-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione hydrochloride
CAS No.	128948-02-7
Molecular Formula	C₃₃H₄₁N₃O₁₁ • HCl
Molecular Weight	Contact for details
Synonyms	Doxorubicin Hydrochloride Impurity; Doxorubicin Related Compound; 8-[N-(Hexan-2-ylideneamino)-C-methyl-carbonimidoyl]-10-[(4-amino-5-hydroxy-6-methyl-oxan-2-yl)oxy]-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione hydrochloride; Anthracycline derivative hydrochloride; Tetracycline-based intermediate; Doxorubicin analog; AD 32 Impurity; 128948-02-7
EINECS	Contact for details

Quality Control

Our 10-(4-amino-5-hydroxy-6-methyl-oxan-2-yl)oxy-8-[N-(hexan-2-ylideneamino)-C-methyl-carbonimidoyl]-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under low-light conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Unknown Impurity	≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.