Description

[(8S,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-methoxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate is a high-purity synthetic steroid derivative of significant interest in advanced pharmaceutical research and development. This compound is valued for its potential as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of steroidal drugs targeting inflammation, hormonal regulation, or other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potent corticosteroid or other steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in preclinical and clinical research to investigate new drug candidates, their metabolic pathways, and structure-activity relationships (SAR).
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development, validation, and impurity profiling of related steroid compounds.
• Process Chemistry: Utilized in scale-up and optimization studies for the development of efficient, GMP-compliant manufacturing processes.
• Biochemical Research: Applied in studies exploring steroid receptor binding affinity and the modulation of specific biological pathways.

Basic Information

Product Name	[(8S,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-methoxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
CAS No.	123013-22-9
Molecular Formula	C₂₈H₃₇FO₆
Molecular Weight	476.59 g/mol
Synonyms	9-Fluoro-11β,17-dihydroxy-17-(2-methoxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl propionate; 17-Propionyloxy-9-fluoro-11β-hydroxy-17-(2-methoxyacetyl)-10,13,16-trimethyl-3-oxo-1,4-androstadiene; Fluorometholone related compound; Steroid intermediate 123013-22-9; 9α-Fluoro-11β-hydroxy-17α-(2-methoxyacetyl)-10β,13β,16β-trimethyl-3-oxo-1,4-androstadiene-17β-yl propionate
EINECS	Contact for details

Quality Control

Our [(8S,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-methoxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, related substances, and other critical parameters are provided and can be tailored to meet client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.